1-alkenyl-2-acylglycerol choline phosphotransferase
| 1-alkenyl-2-acylglycerol choline phosphotransferase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC number | 2.7.8.22 | ||||||
| CAS number | 113066-36-7 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a 1-alkenyl-2-acylglycerol choline phosphotransferase (EC 2.7.8.22) is an enzyme that catalyzes the chemical reaction
- CDP-choline + 1-alkenyl-2-acylglycerol
CMP + plasmenylcholine
Thus, the two substrates of this enzyme are CDP-choline and 1-alkenyl-2-acylglycerol, whereas its two products are CMP and plasmenylcholine.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase. This enzyme is also called CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase. This enzyme participates in ether lipid metabolism.
References
- Wientzek M, Man RY, Choy PC (1987). "Choline glycerophospholipid biosynthesis in the guinea pig heart". Biochem. Cell Biol. 65 (10): 860–8. doi:10.1139/o87-112. PMID 3447597.